JCM Accepts, published online ahead of print on 21 October 2009
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J. Clin. Microbiol. doi:10.1128/JCM.00866-09
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Subtyping of emm1 group A streptococci causing invasive infections in France

P. Bidet, E. Lesteven, C. Doit, S. Liguori, P. Mariani-Kurkdjian, S. Bonacorsi, and E. Bingen*

Université Paris VII, UFR médicale; EA 3105, laboratoire d'Études de Génétique Bactérienne dans les Infections de l'Enfant; Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Microbiologie, Laboratoire associé au CNR des Streptocoques – Infections à Streptocoque du groupe A de l'enfant, Hôpital Robert Debré, Paris, France

* To whom correspondence should be addressed. Email: edouard.bingen{at}rdb.aphp.fr.


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Abstract

By combining PCR amplification of toxin-encoding genes and sic gene sequencing, we distinguished 24 genotypes among 47 M/emm1 group A streptococci isolated in France from children with invasive infections, comprising four clusters (nine cases) and 38 unrelated cases used as controls.