JCM Accepts, published online ahead of print on 21 October 2009
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J. Clin. Microbiol. doi:10.1128/JCM.00605-09
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

THE PREVALENCE AND GENOTYPES OF HELICOBACTER PYLORI IN THE GASTRIC BIOPSY SPECIMENS FROM PATIENTS WITH GASTRODUODENAL PATHOLOGIES IN CUKUROVA REGION, TURKEY

Togrul NAGIYEV, Erkan YULA, Bahri ABAYLI, and Fatih KOKSAL

Department of Microbiology, Faculty of Medicine, University of Cukurova, and Department of Gastroenterology, Adana Cukurova Governmental Hospital, Adana, Turkey


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Abstract

The effects of H. pylori genotypes on clinical prognosis in Cukurova region, Turkey were investigated by PCR. The prevalence of Type-I strains carrying s1c allele, unlike neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcer (P=0.001), and s1a allele in patients with duodenal ulcer (P<0.001). The cagA gene was strongly associated with the more virulent vacA genotypes (P<0.001).






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