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JCM Accepts, published online ahead of print on 7 May 2008
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J. Clin. Microbiol. doi:10.1128/JCM.00313-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Eight years' experience of molecular identification of human enteroviruses

Soile Blomqvist*, Anja Paananen, Carita Savolainen-Kopra, Tapani Hovi, and Merja Roivainen

Enterovirus Laboratory, Department of Viral Diseases and Immunology, National Public Health Institute (KTL), Helsinki, Finland

* To whom correspondence should be addressed. Email: soile.blomqvist{at}ktl.fi.


  Abstract

We have successfully typed 1121 human enterovirus (HEV) isolates during last eight years by adapting partial VP1 sequencing to routine identification of HEV isolated from diverse clinical and environmental specimens. The isolates include 48 of the 59 traditional non-poliovirus HEV serotypes and members of eight newly discovered types, which would have remained untypable by neutralization using the conventional cross-sectional pools of antisera.




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