JCM Accepts, published online ahead of print on 21 October 2009
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J. Clin. Microbiol. doi:10.1128/JCM.00305-09
Copyright (c) 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Rhizomucor variabilis var regularior and Hormographiella aspergillata Infections in a Leukemic Bone Marrow Transplant Recipient with Refractory Neutropenia

Mayssa M. Abuali*, Roberto Posada, Gustavo Del Toro, Elizabeth Roman, Rama Ramani, Sudha Chaturvedi, Vishnu Chaturvedi, and Vincent J. LaBombardi

Pediatric Infectious Diseases, Jack Martin Division of Pediatric Hematology-Oncology, and Microbiology Laboratory, Mount Sinai Medical Center, New York, NY; and Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY

* To whom correspondence should be addressed. Email: mayssa.abu-ali{at}mssm.edu.


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Abstract

Rhizomucor variabilis and Hormographiella aspergillata rarely cause human infections. This report details a fatal case in a 14 year old female with leukemia post hematopoietic cell transplant and relapse with refractory pancytopenia. The patient first developed R. variabilis var. variabilis palate infection and later developed a cutaneous H. aspergillata infection while on posaconazole and caspofungin therapy.