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Journal of Clinical Microbiology, August 2008, p. 2780-2782, Vol. 46, No. 8
0095-1137/08/$08.00+0     doi:10.1128/JCM.00557-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Evaluation of StrepB Carrot Broth versus Lim Broth for Detection of Group B Streptococcus Colonization Status of Near-Term Pregnant Women

Calgary Laboratory Services,¹ Departments of Pathology & Medicine,² Medicine,³ Family Medicine, Calgary Health Region and the University of Calgary, Calgary, Alta., Canada⁴

Received 24 March 2008/ Returned for modification 6 May 2008/ Accepted 27 May 2008

The performance of StrepB Carrot Broth (SCB) versus group B Lim broth (LIM) for detection of group B streptococcus (GBS) colonization status in near-term pregnant women (35 to 37 weeks of gestation) was evaluated. Dually collected vaginal/rectal swabs from 279 women enrolled from a single large maternity clinic were analyzed. Fifty (18%) women were colonized by GBS according to both methods. SCB had excellent diagnostic performance compared to LIM, with sensitivity, specificity, positive predictive value, and negative predictive value of 92%, 100%, 100%, and 98.3%, respectively. Improved diagnostic efficiency due to direct reporting of GBS cases based on an orange color change in the SCB decreased overall labor and material costs.

Published ahead of print on 4 June 2008.